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Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancer.

A method based on the polymerase chain reaction is described for constructing a clustered set of basepair changes, deletions, or insertions at any site on a DNA fragment. Advantages of the procedure are that virtually every product has the desired sequence alteration and that only a single round of...

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Autors principals: Zaret, K S, Liu, J K, DiPersio, C M
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC54346/
https://ncbi.nlm.nih.gov/pubmed/2371282
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