Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B

AIM: To determine the role of hepatitis B virus X protein (HBx), HBx in regulating hepatic progenitor cell (HPC)-like features in hepatocellular carcinoma (HCC) and the underlying molecular mechanisms. METHODS: We used a retrovirus vector to introduce wild type HBx or empty vector into HepG2 cells....

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Publicat a:World J Gastroenterol
Autors principals: Wang, Xuyang, Oishi, Naoki, Shimakami, Tetsuro, Yamashita, Taro, Honda, Masao, Murakami, Seishi, Kaneko, Shuichi
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2017
Matèries:
Basic Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434430/
https://ncbi.nlm.nih.gov/pubmed/28566884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i18.3252
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