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Lithium increases synaptic GluA2 in hippocampal neurons by elevating the δ-catenin protein

Lithium (Li(+)) is a drug widely employed for treating bipolar disorder, however the mechanism of action is not known. Here we study the effects of Li(+) in cultured hippocampal neurons on a synaptic complex consisting of δ-catenin, a protein associated with cadherins whose mutation is linked to aut...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Farooq, Mobeen, Kim, Seonil, Patel, Sunny, Khatri, Latika, Hikima, Takuya, Rice, Margaret E., Ziff, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434258/
https://ncbi.nlm.nih.gov/pubmed/27793771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.10.025
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