Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway

Recent studies indicate that mitochondrial pathways of apoptosis are potential chemotherapeutic target for the treatment of esophageal cancer. Azoxystrobin (AZOX), a methoxyacrylate derived from the naturally occurring strobilurins, is a known fungicide acting as a ubiquinol oxidation (Qo) inhibitor...

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Vydáno v:Front Pharmacol
Hlavní autoři: Shi, Xiao-ke, Bian, Xiao-bo, Huang, Tao, Wen, Bo, Zhao, Ling, Mu, Huai-xue, Fatima, Sarwat, Fan, Bao-min, Bian, Zhao-xiang, Huang, Lin-fang, Lin, Cheng-yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434151/
https://ncbi.nlm.nih.gov/pubmed/28567017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00277
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