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A genetic screen in combination with biochemical analysis in Saccharomyces cerevisiae indicates that phenazine-1-carboxylic acid is harmful to vesicular trafficking and autophagy

The environmentally friendly antibiotic phenazine-1-carboxylic acid (PCA) protects plants, mammals and humans effectively against various fungal pathogens. However, the mechanism by which PCA inhibits or kills fungal pathogens is not fully understood. We analyzed the effects of PCA on the growth of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Xiaolong, Zeng, Yan, Zhao, Xiu, Zou, Shenshen, He, Ya-Wen, Liang, Yongheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434042/
https://ncbi.nlm.nih.gov/pubmed/28512289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01452-6
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