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Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity

The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very similar cysteine-rich antifungal proteins from ascomycetes provide a feasible basis for designing new antifungal molecules. The main structural...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Galgóczy, László, Borics, Attila, Virágh, Máté, Ficze, Hargita, Váradi, Györgyi, Kele, Zoltán, Marx, Florentine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434006/
https://ncbi.nlm.nih.gov/pubmed/28512317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02234-w
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