The percentage of Epidermal Growth Factor Receptor (EGFR)-mutated neoplastic cells correlates to response to tyrosine kinase inhibitors in lung adenocarcinoma

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) molecular analysis is performed to assess the responsiveness to Tyrosine Kinase Inhibitors (TKIs) in patients with Non-Small Cell Lung Cancer (NSCLC). The existence of molecular intra-tumoral heterogeneity has been observed in lung cancers. The aim...

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Publicado en:PLoS One
Main Authors: de Biase, Dario, Genestreti, Giovenzio, Visani, Michela, Acquaviva, Giorgia, Di Battista, Monica, Cavallo, Giovanna, Paccapelo, Alexandro, Cancellieri, Alessandra, Trisolini, Rocco, Degli Esposti, Roberta, Bartolini, Stefania, Pession, Annalisa, Tallini, Giovanni, Brandes, Alba A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433779/
https://ncbi.nlm.nih.gov/pubmed/28520821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177822
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