Different Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naïve and Treated Indonesian Patients Infected with Hepatitis B Virus

A nucleos(t)ide analog (NA) is the common antiviral drug available for directly treating hepatitis B virus (HBV) infection. However, its application has led to the emergence of NA-resistant mutations mostly in a conserved region of the reverse transcriptase domain of HBV polymerase. Harboring NA-res...

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Publicado en:Kobe J Med Sci
Autores principales: WASITYASTUTI, WIDYA, YANO, YOSHIHIKO, WIDASARI, DEWIYANI INDAH, YAMANI, LAURA NAVIKA, RATNASARI, NENENG, HERIYANTO, DIDIK SETYO, OKADA, RINA, TANAHASHI, TOSHIHITO, MURAKAMI, YOSHIKI, AZUMA, TAKESHI, HAYASHI, YOSHITAKE
Formato: Artigo
Lenguaje:Inglês
Publicado: Kobe University School Of Medicine 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433726/
https://ncbi.nlm.nih.gov/pubmed/27492206
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