Genetic polymorphisms of N-acetyltransferase 2 & susceptibility to antituberculosis drug-induced hepatotoxicity

BACKGROUND & OBJECTIVES: The N-acetyltransferase 2 (NAT2) gene encodes an enzyme which both activates and deactivates arylamine and other drugs and carcinogens. This study was aimed to investigate the role of NAT2 gene polymorphism in anti-tuberculosis drug-induced hepatotoxicity (DIH). METHODS:...

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Bibliografiske detaljer
Udgivet i:Indian J Med Res
Main Authors: Sharma, Surendra K., Jha, Brajesh Kumar, Sharma, Abhishek, Sreenivas, V., Upadhyay, Vishwanath, Jaisinghani, Chandrita, Singla, Rohit, Mishra, Hemant Kumar, Soneja, Manish
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433286/
https://ncbi.nlm.nih.gov/pubmed/28474630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijmr.IJMR_684_14
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