An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets

BACKGROUND: A microRNA (miRNA) collection on the imprinted 14q32 MEG3 region has been associated with outcome in osteosarcoma. We assessed the clinical utility of this miRNA set and their association with methylation status. METHODS: We integrated coding and non-coding RNA data from three independen...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Hematol Oncol
Main Authors: Hill, Katherine E., Kelly, Andrew D., Kuijjer, Marieke L., Barry, William, Rattani, Ahmed, Garbutt, Cassandra C., Kissick, Haydn, Janeway, Katherine, Perez-Atayde, Antonio, Goldsmith, Jeffrey, Gebhardt, Mark C., Arredouani, Mohamed S., Cote, Greg, Hornicek, Francis, Choy, Edwin, Duan, Zhenfeng, Quackenbush, John, Haibe-Kains, Benjamin, Spentzos, Dimitrios
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2017
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433149/
https://ncbi.nlm.nih.gov/pubmed/28506242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0465-4
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