Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2

The hepatitis C virus (HCV) glycoprotein E2 is the major target of neutralizing antibodies and is therefore highly relevant for vaccine design. Its structure features a central immunoglobulin (Ig)-like β-sandwich that contributes to the binding site for the cellular receptor CD81. We show that a syn...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Vasiliauskaite, Ieva, Owsianka, Ania, England, Patrick, Khan, Abdul Ghafoor, Cole, Sarah, Bankwitz, Dorothea, Foung, Steven K. H., Pietschmann, Thomas, Marcotrigiano, Joseph, Rey, Felix A., Patel, Arvind H., Krey, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433095/
https://ncbi.nlm.nih.gov/pubmed/28512091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00382-17
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