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Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB

Osteoarthritis (OA) is a multi-factorial and highly prevalent joint disorder worldwide. Since the establishment of murine surgical knee OA models in 2005, many of the key molecules and signalling pathways responsible for OA development have been identified. Here we review the roles of two multi-func...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Saito, Taku, Tanaka, Sakae
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433029/
https://ncbi.nlm.nih.gov/pubmed/28506315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1296-y
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