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Does the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor differ according to the type of EGFR mutation in non-small cell lung cancer?

An exon 19 deletion and a L858R mutation in exon 21 of the epidermal growth factor receptor (EGFR) are the two most common mutations that predict favorable efficacy of EGFR tyrosine kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC). Many retrospective and prospective studi...

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Detalhes bibliográficos
Publicado no:Korean J Intern Med
Main Authors: Choi, Yong Won, Choi, Jin-Hyuk
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Internal Medicine 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432802/
https://ncbi.nlm.nih.gov/pubmed/28352061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2016.190
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