Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment

Deregulated Sonic Hedgehog (SHH) pathway facilitates the initiation, progression, and metastasis of Non-small cell lung cancer (NSCLC), confers drug resistance and renders a therapeutic interference option to lung cancer patients with poor prognosis. In this study, we screened and evaluated the spec...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Du, Jing, Chen, Weiwei, Yang, Lijuan, Dai, Juanjuan, Guo, Jiwei, Wu, Yan, Gong, Kaikai, Zhang, Jian, Yu, Ning, Xie, Zhen, Xi, Sichuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432500/
https://ncbi.nlm.nih.gov/pubmed/28507311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02063-x
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