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A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC
Panobinostat (pano) is an FDA-approved histone deacetylase inhibitor. There is interest in evaluating alternate dosing schedules and novel combinations of pano for the treatment of upper aerodigestive and lung malignancies; thus we evaluated it in combination with Taxol, a chemotherapeutic with acti...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432488/ https://ncbi.nlm.nih.gov/pubmed/28507307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01964-1 |
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