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Improvement of dexamethasone sensitivity by chelation of intracellular Ca(2+) in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation

Previous studies have demonstrated that glucocorticoid hormones, including dexamethasone, induced alterations in intracellular calcium homeostasis in acute lymphoblastic leukemia (ALL) cells. However, the mechanism by which intracellular calcium homeostasis participates in dexamethasone sensitivity...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Abdoul-Azize, Souleymane, Dubus, Isabelle, Vannier, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432339/
https://ncbi.nlm.nih.gov/pubmed/28423696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16039
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