Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling

Higher levels of hyaluronan (HA) and its receptors CD44 and RHAMM have been associated with poor prognosis and metastasis in NSCLC. In the current study, our goal was to define, using cellular and orthotopic lung tumor models, the role of HA-CD44/RHAMM signaling in lung carcinogenesis and to assess...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Song, Jung Min, Molla, Kalkidan, Anandharaj, Arunkumar, Cornax, Ingrid, O`Sullivan, M. Gerard, Kirtane, Ameya R., Panyam, Jayanth, Kassie, Fekadu
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432308/
https://ncbi.nlm.nih.gov/pubmed/28460475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15879
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