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Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer

CDC42 is an oncogenic Rho GTPase overexpressed in colorectal cancer (CRC). Although CDC42 has been shown to regulate gene transcription, the specific molecular mechanisms regulating the oncogenic ability of CDC42 remain unknown. Here, we have characterized the transcriptional networks governed by CD...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Valdés-Mora, Fatima, Locke, Warwick J., Bandrés, Eva, Gallego-Ortega, David, Cejas, Paloma, García-Cabezas, Miguel Angel, Colino-Sanguino, Yolanda, Feliú, Jaime, del Pulgar, Teresa Gómez, Lacal, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432295/
https://ncbi.nlm.nih.gov/pubmed/28460460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15815
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