Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H(4) receptor agonists and opportunity for combination with radiation

The aims of the work were to improve our knowledge of the role of H(4)R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H(4)R agonist, in a preclinical metastatic model of melanoma. Additionally, we aimed to investigate the combinator...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Massari, Noelia A., Nicoud, Melisa B., Sambuco, Lorena, Cricco, Graciela P., Lamas, Diego J. Martinel, Ducloux, María V. Herrero, Blanco, Horacio, Rivera, Elena S., Medina, Vanina A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432273/
https://ncbi.nlm.nih.gov/pubmed/28460440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15594
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