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Macrophage Integrins Modulate Response to Ultra-High Molecular Weight Polyethylene Particles and Direct Particle-Induced Osteolysis

Aseptic loosening due to peri-prosthetic osteolysis is one of the primary causes for failure of artificial joint replacements. Implant-derived wear particles, often ultra-high molecular weight polyethylene (UHMWPE) microparticles, initiate an inflammatory cascade upon phagocytosis by macrophages, wh...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Zaveri, Toral D., Dolgova, Natalia V., Lewis, Jamal S., Hamaker, Kiri, Clare-Salzler, Michael J., Keselowsky, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431751/
https://ncbi.nlm.nih.gov/pubmed/27889664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.10.038
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