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In vivo and in vitro ageing results in accumulation of de novo copy number variations in bulls

We have identified de novo copy number variations (CNVs) generated in bulls as they age. Blood samples from eight bulls were collected and SNP arrayed in a prospective design over 30 months allowing us to differentiate de novo CNVs from constant CNVs that are present throughout the sampling period....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Revay, Tamas, Oluwole, Olutobi, Kroetsch, Tom, King, W. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431667/
https://ncbi.nlm.nih.gov/pubmed/28487564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01793-2
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