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Increased MIR31HG lncRNA expression increases gefitinib resistance in non-small cell lung cancer cell lines through the EGFR/PI3K/AKT signaling pathway

The aim of the present study was to gain insight into the molecular mechanism of gefitinib resistance in non-small cell lung cancer (NSCLC), and demonstrate whether long noncoding RNA (lncRNA) expression signatures differ between gefitinib-sensitive PC9 and gefitinib-resistant PC9 (PC9-R) cell lines...

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Bibliografische gegevens
Gepubliceerd in:Oncol Lett
Hoofdauteurs: Wang, Bing, Jiang, Hong, Wang, Limin, Chen, Xueqin, Wu, Kan, Zhang, Shirong, Ma, Shenglin, Xia, Bing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431660/
https://ncbi.nlm.nih.gov/pubmed/28529576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5878
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