Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin

Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruptions to the intestinal epithelial barrier and translocation of bacteria, resulting in inflammation, are common in colitis. The mechanisms underlying epithelial barrier dysfunction or regulation of tight...

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Pubblicato in:Sci Rep
Autori principali: Chelakkot, Chaithanya, Ghim, Jaewang, Rajasekaran, Nirmal, Choi, Jong-Sun, Kim, Jung-Hwan, Jang, Myoung Ho, Shin, Young Kee, Suh, Pann-Ghill, Ryu, Sung Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431506/
https://ncbi.nlm.nih.gov/pubmed/28484281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01797-y
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