Expression and characterization of an antibody binding specificity joined to insulin-like growth factor 1: potential applications for cellular targeting.
To create antibody molecules with improved functional properties, a growth factor (insulin-like growth factor 1, IGF1) was used to replace the constant region of a chimeric mouse-human IgG3 anti-dansyl antibody. The chimeric heavy chain was expressed with an anti-dansyl-specific chimeric kappa light...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2115168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5322 |
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