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DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer

High-grade serous ovarian cancer is the most common ovarian cancer type. Although the combination of surgery and platinum-taxane chemotherapy provide an effective treatment, drug resistance frequently occurs leading to poor outcome. In order to clarify the molecular mechanisms of drug resistance, th...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Lund, Riikka J., Huhtinen, Kaisa, Salmi, Jussi, Rantala, Juha, Nguyen, Elizabeth V., Moulder, Robert, Goodlett, David R., Lahesmaa, Riitta, Carpén, Olli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431431/
https://ncbi.nlm.nih.gov/pubmed/28473707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01624-4
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