Inhibition of MMP-9 expression by ritonavir or saquinavir is associated with inactivation of the AKT/Fra-1 pathway in cervical intraepithelial neoplasia cells

A reduced incidence and decreased clinical progression of uterine cervical intraepithelial neoplasia (CIN) has been observed in women infected with human immunodeficiency virus (HIV) treated with HIV-protease inhibitors (PIs). The HIV-PIs saquinavir (SQV) and ritonavir (RTV) have been demonstrated t...

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Publicado en:Oncol Lett
Main Authors: Bacigalupo, Ilaria, Palladino, Clelia, Leone, Patrizia, Toschi, Elena, Sgadari, Cecilia, Ensoli, Barbara, Barillari, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2017
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431249/
https://ncbi.nlm.nih.gov/pubmed/28521396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5835
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