Mucin-1-Antibody-Conjugated Mesoporous Silica Nanoparticles for Selective Breast Cancer Detection in a Mucin-1 Transgenic Murine Mouse Model

Mucin-1 (MUC1), a transmembrane glycoprotein is aberrantly expressed on ~90% of breast cancer and is an excellent target for nanoparticulate targeted imaging. In this study, the development of a dye-doped NIR emitting mesoporous silica nanoparticles platform conjugated to tumor-specific MUC1 antibod...

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Udgivet i:J Biomed Nanotechnol
Main Authors: Dréau, Didier, Moore, Laura Jeffords, Alvarez-Berrios, Merlis P., Tarannum, Mubin, Mukherjee, Pinku, Vivero-Escoto, Juan L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431076/
https://ncbi.nlm.nih.gov/pubmed/28522938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/jbn.2016.2318
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