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Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility, dissolution and permeability across intestinal barrier are the key parameters controlling absorption. This rev...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: B. Shekhawat, Prachi, B. Pokharkar, Varsha
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430883/
https://ncbi.nlm.nih.gov/pubmed/28540164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.09.005
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