Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain

Spreading depolarizations (SDs) occur spontaneously in the cerebral cortex of subarachnoid hemorrhage, stroke or traumatic brain injury patients. Accumulating evidence prove that SDs exacerbate focal ischemic injury by converting zones of the viable but non-functional ischemic penumbra to the core r...

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Udgivet i:Sci Rep
Main Authors: Menyhárt, Ákos, Zölei-Szénási, Dániel, Puskás, Tamás, Makra, Péter, Orsolya, M. Tóth, Szepes, Borbála É., Tóth, Réka, Ivánkovits-Kiss, Orsolya, Obrenovitch, Tihomir P., Bari, Ferenc, Farkas, Eszter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430878/
https://ncbi.nlm.nih.gov/pubmed/28442781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01284-4
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