Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients

The aim of the research was to investigate the pharmacokinetics (PK) of enteric-coated mycophenolate sodium (EC-MPS) by quantification of the active metabolite of mycophenolic acid (MPA) after multiple escalating oral doses in Han kidney transplant recipients. A total of 28 Han postoperative kidney...

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Publicado en:Acta Pharm Sin B
Autores principales: Zhang, Jun, Jia, Mengmeng, Zuo, Lihua, Li, Na, Luo, Yonggang, Sun, Zhi, Zhang, Xiaojian, Zhu, Zhenfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430868/
https://ncbi.nlm.nih.gov/pubmed/28540172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.11.003
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