Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice

Inflammatory processes in brain tissue have been described in human epilepsy of various etiologies and in experimental models of seizures. High mobility group box-1 (HMGB1) is now recognized as representative of damage-associated molecular patterns (DAMPs). In the present study, we focused on whethe...

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Vydáno v:Sci Rep
Hlavní autoři: Fu, Li, Liu, Keyue, Wake, Hidenori, Teshigawara, Kiyoshi, Yoshino, Tadashi, Takahashi, Hideo, Mori, Shuji, Nishibori, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430706/
https://ncbi.nlm.nih.gov/pubmed/28446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01325-y
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