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Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice

The strict species specificity of Human Cytomegalovirus (HCMV) has impeded our understanding of antiviral adaptive immune responses in the context of a human immune system. We have previously shown that HCMV infection of human hematopoietic progenitor cells engrafted in immune deficient mice (huNSG)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Crawford, Lindsey B., Tempel, Rebecca, Streblow, Daniel N., Kreklywich, Craig, Smith, Patricia, Picker, Louis J., Nelson, Jay A., Caposio, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430540/
https://ncbi.nlm.nih.gov/pubmed/28428537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01051-5
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