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An insulin response element in the glyceraldehyde-3-phosphate dehydrogenase gene binds a nuclear protein induced by insulin in cultured cells and by nutritional manipulations in vivo.

Two independent cis-acting insulin response elements (IREs) in the gene encoding glyceraldehyde-3-phosphate dehydrogenase [D-glyceraldehyde-3-phosphate: NAD+ oxidoreductase (phosphorylating), EC 1.2.1.12], designated IRE-A and IRE-B, are sufficient to direct insulin-inducible gene expression. Using...

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Detalhes bibliográficos
Main Authors: Nasrin, N, Ercolani, L, Denaro, M, Kong, X F, Kang, I, Alexander, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54305/
https://ncbi.nlm.nih.gov/pubmed/2164673
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