Mutations in the Hco-mptl-1 gene in a field-derived monepantel-resistant isolate of Haemonchus contortus()

Resistance to the anthelmintic drug monepantel (Zolvix(®)) has emerged in parasitic worms infecting sheep and goats. The mechanism of resistance in these cases is unknown. The drug targets nicotinic acetylcholine receptors belonging to the nematode-specific DEG-3 subfamily. We examined the receptor...

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Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Bagnall, Neil H., Ruffell, Angela, Raza, Ali, Elliott, Timothy P., Lamb, Jane, Hunt, Peter W., Kotze, Andrew C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430491/
https://ncbi.nlm.nih.gov/pubmed/28501715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.05.001
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