Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo

The fidelity of synaptic transmission depends on the integrity of the protein machinery at the synapse. Unfolded synaptic proteins undergo refolding or degradation in order to maintain synaptic proteostasis and preserve synaptic function, and buildup of unfolded/toxic proteins leads to neuronal dysf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deng, Jingti, Koutras, Carolina, Donnelier, Julien, Alshehri, Mana, Fotouhi, Maryam, Girard, Martine, Casha, Steve, McPherson, Peter S., Robbins, Stephen M., Braun, Janice E. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430488/
https://ncbi.nlm.nih.gov/pubmed/28424476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01115-6
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