Paraquat poisoning induced pulmonary epithelial mesenchymal transition through Notch1 pathway

Progressive pulmonary fibrosis is the most characteristic feature of subacute PQ poisoning. Epithelial-to-mesenchymal transition (EMT) is reported to be involved in the pulmonary fibrosis after PQ exposure. Recent evidence suggested Notch signaling is required for EMT. In this study, we investigated...

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Udgivet i:Sci Rep
Main Authors: Li, Tiegang, Yang, Xiangming, Xin, Shiyu, Cao, Yan, Wang, Nana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430447/
https://ncbi.nlm.nih.gov/pubmed/28424456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01069-9
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