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Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers

Protein-folding stress at the Endoplasmic Reticulum (ER) occurs in the hypothalamus during diet-induced obesity (DIO) and is linked to metabolic disease development. ER stress is buffered by the activation of the unfolded protein response (UPR), a controlled network of pathways inducing a set of gen...

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Publicat a:Front Neurosci
Autors principals: Belegri, Evita, Rijnsburger, Merel, Eggels, Leslie, Unmehopa, Unga, Scheper, Wiep, Boelen, Anita, la Fleur, Susanne E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430050/
https://ncbi.nlm.nih.gov/pubmed/28555094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00270
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