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An Influenza HA and M2e Based Vaccine Delivered by a Novel Attenuated Salmonella Mutant Protects Mice against Homologous H1N1 Infection

Attenuated Salmonella strains constitute a promising technology for the development of a more efficient multivalent protein based vaccines. In this study, we constructed a novel attenuated strain of Salmonella for the delivery and expression of the H1N1 hemagglutinin (HA) and the conserved extracell...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Hajam, Irshad A., Lee, John H.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430049/
https://ncbi.nlm.nih.gov/pubmed/28555133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00872
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