Induction of Steatohepatitis (NASH) with Insulin Resistance in Wild-type B6 Mice by a Western-type Diet Containing Soybean Oil and Cholesterol

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are hepatic manifestations of the metabolic syndrome. Many currently used animal models of NAFLD/NASH lack clinical features of either NASH or metabolic syndrome such as hepatic inflammation and fibrosis (e.g., high-fat...

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Publicado en:Mol Med
Main Authors: Henkel, Janin, Coleman, Charles Dominic, Schraplau, Anne, Jöhrens, Korinna, Weber, Daniela, Castro, José Pedro, Hugo, Martin, Schulz, Tim Julius, Krämer, Stephanie, Schürmann, Annette, Püschel, Gerhard Paul
Formato: Artigo
Idioma:Inglês
Publicado: Feinstein Institute for Medical Research 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429885/
https://ncbi.nlm.nih.gov/pubmed/28332698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00203
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