Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression

Exposure of human monocytes to lipopolysaccharide (LPS) induces a temporary insensitivity to subsequent LPS challenges, a cellular state called endotoxin tolerance. In this study, we investigated the LPS-induced global glycoprotein expression changes of tolerant human monocytes and THP-1 cells to id...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Müller, Mario M., Lehmann, Roland, Klassert, Tilman E., Reifenstein, Stella, Conrad, Theresia, Moore, Christoph, Kuhn, Anna, Behnert, Andrea, Guthke, Reinhard, Driesch, Dominik, Slevogt, Hortense
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429802/
https://ncbi.nlm.nih.gov/pubmed/28404994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00828-y
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