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LPS promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latency

Human cytomegalovirus (HCMV) infection of myeloid cells is closely linked with the differentiation status of the cell. Haematopoietic progenitors and CD14+ monocytes are usually non-permissive for lytic gene expression which can lead to the establishment of latent infections. In contrast, differenti...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kew, V. G., Wills, M. R., Reeves, M. B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429787/
https://ncbi.nlm.nih.gov/pubmed/28400599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00999-8
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