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PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NFκB

Phosphotyrosine Interaction Domain containing 1 (PID1; NYGGF4) inhibits growth of medulloblastoma, glioblastoma and atypical teratoid rhabdoid tumor cell lines. PID1 tumor mRNA levels are highly correlated with longer survival in medulloblastoma and glioma patients, suggesting their tumors may have...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Jingying, Ren, Xiuhai, Pathania, Anup Singh, Fernandez, G. Esteban, Tran, Anthony, Zhang, Yifu, Moats, Rex A., Shackleford, Gregory M., Erdreich-Epstein, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429784/
https://ncbi.nlm.nih.gov/pubmed/28400607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00947-6
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