Sodium fluoride induces nephrotoxicity via oxidative stress-regulated mitochondrial SIRT3 signaling pathway

Accumulation of mitochondrial reactive oxygen species (mROS) has been implicated in the pathogenesis of fluorosis. As the main mitochondrial deacetylase, SIRT3 is closely associated with oxidative stress. To investigate the role of SIRT3 in response to sodium fluoride (NaF)-induced nephrotoxicity. O...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Song, Chao, Fu, Beibei, Zhang, Jingcheng, Zhao, Jiamin, Yuan, Mengke, Peng, Wei, Zhang, Yong, Wu, Haibo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429606/
https://ncbi.nlm.nih.gov/pubmed/28386112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00796-3
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