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Effects of annulus defects and implantation of poly(lactic-co-glycolic acid) (PLGA)/fibrin gel scaffolds on nerves ingrowth in a rabbit model of annular injury disc degeneration

BACKGROUND: Growth of nerve fibers has been shown to occur in a rabbit model of intravertebral disc degeneration (IVD) induced by needle puncture. As nerve growth may underlie the process of chronic pain in humans affected by disc degeneration, we sought to investigate the factors underlying nerve i...

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Detalhes bibliográficos
Publicado no:J Orthop Surg Res
Main Authors: Xin, Long, Xu, Weixing, Yu, Leijun, Fan, Shunwu, Wang, Wei, Yu, Fang, Wang, Zhenbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429511/
https://ncbi.nlm.nih.gov/pubmed/28499451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-017-0572-5
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