Crosstalk between HDAC6 and Nox2-based NADPH oxidase mediates HIV-1 Tat-induced pro-inflammatory responses in astrocytes

Histone deacetylase 6 (HDAC6) likely is important in inflammatory diseases. However, how HDAC6 exerts its effect on inflammatory processes remains unclear. HIV-1 transactivator of transcription (Tat) activates NADPH oxidase resulting in generation of reactive oxygen species (ROS), leading to extensi...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Youn, Gi Soo, Cho, Hyundong, Kim, Donggyu, Choi, Soo Young, Park, Jinseu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429231/
https://ncbi.nlm.nih.gov/pubmed/28499252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.001
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