A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis (PBC) is an autoimmune liver disease with a strong hereditary component. Here, we report a genome-wide association study that included 1,122 PBC cases and 4,036 controls of Han Chinese descent, with subsequent replication in a separate cohort of 907 PBC cases and 2,127 co...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Qiu, Fang, Tang, Ruqi, Zuo, Xianbo, Shi, Xingjuan, Wei, Yiran, Zheng, Xiaodong, Dai, Yaping, Gong, Yuhua, Wang, Lan, Xu, Ping, Zhu, Xiang, Wu, Jian, Han, Chongxu, Gao, Yueqiu, Zhang, Kui, Jiang, Yuzhang, Zhou, Jianbo, Shao, Youlin, Hu, Zhigang, Tian, Ye, Zhang, Haiyan, Dai, Na, Liu, Lei, Wu, Xudong, Zhao, Weifeng, Zhang, Xiaomin, Zang, Zhidong, Nie, Jinshan, Sun, Weihao, Zhao, Yi, Mao, Yuan, Jiang, Po, Ji, Hualiang, Dong, Qing, Li, Junming, Li, Zhenzhong, Bai, Xinli, Li, Li, Lin, Maosong, Dong, Ming, Li, Jinxin, Zhu, Ping, Wang, Chan, Zhang, Yanqiu, Jiang, Peng, Wang, Yujue, Jawed, Rohil, Xu, Jing, Zhang, Yu, Wang, Qixia, Yang, Yue, Yang, Fan, Lian, Min, Jiang, Xiang, Xiao, Xiao, Li, Yanmei, Fang, Jingyuan, Qiu, Dekai, Zhu, Zhen, Qiu, Hong, Zhang, Jianqiong, Tian, Wenyan, Chen, Sufang, Jiang, Ling, Ji, Bing, Li, Ping, Chen, Guochang, Wu, Tianxue, Sun, Yan, Yu, Jianjiang, Tang, Huijun, He, Michun, Xia, Min, Pei, Hao, Huang, Lihua, Qing, Zhuye, Wu, Jianfang, Huang, Qinghai, Han, Junhai, Xie, Wei, Sun, Zhongsheng, Guo, Jian, He, Gengsheng, Eric Gershwin, M., Lian, Zhexiong, Liu, Xiang, Seldin, Michael F., Liu, Xiangdong, Chen, Weichang, Ma, Xiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429142/
https://ncbi.nlm.nih.gov/pubmed/28425483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14828
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