Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a slowly-evolving parameter. In contrast, we demonstrate an unexpected flexibility in...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Swings, Toon, Van den Bergh, Bram, Wuyts, Sander, Oeyen, Eline, Voordeckers, Karin, Verstrepen, Kevin J, Fauvart, Maarten, Verstraeten, Natalie, Michiels, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Genomics and Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429094/
https://ncbi.nlm.nih.gov/pubmed/28460660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22939
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