Fast iodide-SAD phasing for high-throughput membrane protein structure determination

We describe a fast, easy, and potentially universal method for the de novo solution of the crystal structures of membrane proteins via iodide–single-wavelength anomalous diffraction (I-SAD). The potential universality of the method is based on a common feature of membrane proteins—the availability a...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Melnikov, Igor, Polovinkin, Vitaly, Kovalev, Kirill, Gushchin, Ivan, Shevtsov, Mikhail, Shevchenko, Vitaly, Mishin, Alexey, Alekseev, Alexey, Rodriguez-Valera, Francisco, Borshchevskiy, Valentin, Cherezov, Vadim, Leonard, Gordon A., Gordeliy, Valentin, Popov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429034/
https://ncbi.nlm.nih.gov/pubmed/28508075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602952
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