Targeting the Canonical NF-κB Pathway with a High Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome

Idiopathic pneumonia syndrome (IPS) is a non-infectious, inflammatory disorder of the lungs that occurs most often after fully myeloablative allogeneic hematopoietic stem cell transplantation (HSCT). IPS can be severe and is associated with high one year mortality rates despite existing therapies. T...

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Detalhes bibliográficos
Publicado no:Biol Blood Marrow Transplant
Main Authors: Fowler, Kenneth A, Jania, Corey M, Tilley, Stephen L, Panoskaltsis-Mortari, Angela, Baldwin, Albert S, Serody, Jonathan S, Coghill, James M
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428988/
https://ncbi.nlm.nih.gov/pubmed/28161607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.01.083
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