Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity

Myogenic stem cells are a promising avenue for the treatment of muscular disorders. Freshly isolated muscle stem cells have a remarkable engraftment ability in vivo, but their cell number is limited. Current conventional culture conditions do not allow muscle stem cells to expand in vitro with their...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sakai, Hiroshi, Fukuda, Sumiaki, Nakamura, Miki, Uezumi, Akiyoshi, Noguchi, Yu-taro, Sato, Takahiko, Morita, Mitsuhiro, Yamada, Harumoto, Tsuchida, Kunihiro, Tajbakhsh, Shahragim, Fukada, So-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428926/
https://ncbi.nlm.nih.gov/pubmed/28498863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177516
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